Peptide science, analysis and evidence
Reference material on peptide chemistry, analytical testing, research evidence and regulation — written to be accurate about what is known and explicit about what is not.
Start here
How to Read a Peptide Certificate of Analysis
A section-by-section guide to COAs: what each figure means, which claims a certificate can support, and the gaps that most often go unnoticed.
Peptide Purity and Identity Testing: Which Method Answers Which Question
RP-HPLC, mass spectrometry, amino-acid analysis and Karl Fischer titration each answer a different question. A guide to choosing and interpreting them.
Peptide Science Glossary
Plain-language definitions of the terms used across peptide chemistry, analysis, pharmacology and regulation — a reference for reading the literature.
Peptide Stability, Degradation and Storage
The chemical routes by which peptides degrade — hydrolysis, oxidation, deamidation, aggregation — and what storage and handling practice follows from them.
Recent articles
12 articles · page 1 of 2
How to Read a Peptide Certificate of Analysis
A section-by-section guide to COAs: what each figure means, which claims a certificate can support, and the gaps that most often go unnoticed.
Incretin Pharmacology: GLP-1, GIP, Glucagon and Amylin Receptors
How the incretin system works, why multi-receptor agonists were developed, and what distinguishes the compounds in this rapidly moving research area.
Mass Spectrometry for Peptide Identification
How ESI and MALDI differ, why multiply charged ions appear, what tandem MS adds over intact mass, and the limits of each approach.
Peptide Classification: Analogues, Conjugates, Mimetics and Complexes
Why a GLP-1 analogue, a copper tripeptide complex and a retro-inverso peptide belong in different categories, and what the distinctions predict about their behaviour.
Peptide Purity and Identity Testing: Which Method Answers Which Question
RP-HPLC, mass spectrometry, amino-acid analysis and Karl Fischer titration each answer a different question. A guide to choosing and interpreting them.
Peptide Reference Standards: What They Are and Why Identity Work Needs Them
The difference between a reference standard, a working standard and an ordinary sample, and why comparison against a characterised material beats a mass measurement.
Peptide Science Glossary
Plain-language definitions of the terms used across peptide chemistry, analysis, pharmacology and regulation — a reference for reading the literature.
Peptide Stability, Degradation and Storage
The chemical routes by which peptides degrade — hydrolysis, oxidation, deamidation, aggregation — and what storage and handling practice follows from them.
Reading Peptide Research: What Animal Studies Can and Cannot Establish
A hierarchy of evidence applied to peptide literature — in-vitro, animal models, observational work and controlled trials — and the failure modes at each level.