PT-141 (bremelanotide)
Also known as: bremelanotide
A melanocortin receptor agonist, structurally related to Melanotan II, which has received marketing authorisation in at least one jurisdiction for a specific indication.
Development status: Approved as a medicine in one or more jurisdictions
Identifiers and molecular characteristics
- CAS number
- Not verified
- Molecular formula
- Not verified
- Molecular mass
- Not verified
- Amino-acid sequence
- Not verified
- PubChem CID
- Not verified
Identifiers are published only with a source and a check date. Fields marked “not verified” have not yet been confirmed against a primary source — we show the gap rather than an unchecked figure. Always confirm against the certificate of analysis for the specific lot you hold.
Biological targets
- MC4R (principal)
- MC1R
Mechanism of action
A metabolite-derived analogue of Melanotan II with a free acid C-terminus. MC4R activity in the central nervous system is the proposed basis for its approved indication.
Research evidence and its limits
Phase 3 clinical programme and regulatory review.
Safety considerations
Where this compound is an approved medicine, the authoritative safety source is the product labelling issued by the relevant regulator — not this page. Research-grade material is not pharmaceutical product and carries none of those assurances. Supplied and discussed here strictly as a laboratory research material. Not a medicine, not for human or veterinary administration, and nothing on this page should be read as a dosing, treatment or safety recommendation.
Analytical identification and quality testing
Identity by high-resolution mass spectrometry against the expected mass, purity by RP-HPLC with UV detection. Tandem MS sequencing or peptide mapping gives stronger identity evidence than mass alone.
Regulatory status
Approved in the United States for a specific indication. Confirm status elsewhere with the relevant authority.
References
Related compounds
Entry last reviewed 2026-10-11. Regulatory status and scientific understanding change; verify against primary sources before relying on anything here.